Profhilo Structura before and after results — mid-face lifting and restoration of superficial fat pads. Courtesy of R. Forte. Pelle Aesthetics Hertford
✦ 95% of patients noticed lasting mid-face improvement

Structural Bio-Remodelling · Hertford, Hertfordshire

Profhilo®
Structura
in Hertford

The most advanced evolution of Profhilo. Using patented NAHYCO® technology, Structura is injected deep into the superficial fat layer — restoring and repositioning the mid-face fat pads that deflate and descend with age, for genuine structural lifting without filler bulk.

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The Treatment

What is
Profhilo Structura?

Profhilo Structura is the latest generation of the Profhilo family — a next-generation injectable treatment that goes beyond skin bio-remodelling to address the structural changes underlying facial ageing.

Developed using patented NAHYCO® technology, Structura stabilises a distinct complex of high and low molecular weight hyaluronic acid without chemical cross-linkers, ensuring the purest possible formulation. When injected into the subcutaneous layer, it activates ageing adipose fat cell receptors — subtly and safely encouraging them to behave as they did in youth.

The result is a clinically proven restoration of superficial fat to its original position — addressing the hollowing, descent, and squaring of the mid-face that no skin-level treatment can reach.

At Pelle Aesthetics

Structural lifting,
precisely targeted

Profhilo Structura is injected in the preauricular area — the upper cheek region — using a carefully evaluated protocol that takes into account mid-face projection, hollows, skin laxity, and tissue density. This is not a generalised injection: the assessment and placement are as important as the product itself.

The treatment consists of two sessions, one month apart. Results are fast-acting and continue to develop as the treatment works at a cellular level, with 95% of patients noticing lasting improvement in the mid-face area — sustained three months after treatment.

Dr Sabrina

GMC-Registered GP  ·  Founder & Lead Clinician, Pelle Aesthetics
Hertford, Hertfordshire

95%

of patients noticed lasting mid-face improvement after the first treatment

3 months

improvement sustained at the 3-month follow-up in clinical trials

NAHYCO®

patented thermal technology — no chemical cross-linkers required

Deeper

injected into subcutaneous layer to target fat pads directly

The Mechanism

How Structura
restores the mid-face

01

Deep Injection Protocol

Dr Sabrina injects Profhilo Structura into the preauricular area using a protocol that evaluates your individual facial structure — mid-face projection, hollows, laxity, and skin density — before each session.

02

Fat Cell Activation

Structura reaches the superficial fat pads and activates ageing adipose fat cell receptors. These receptors are stimulated to behave as they did in youth — restoring the fat pad's natural volume, position, and support function.

03

Fat Pad Repositioning

As the fat cells respond, the superficial fat pads are clinically proven to be restored to their original position — reversing the hollowing and descent that characterises mid-face ageing and creates a flatter, squarer facial profile.

04

Progressive Results

Results develop over weeks following each session. Two treatments are administered one month apart. The full structural improvement — improved cheek definition, reduced hollows, a more lifted facial contour — is visible within weeks of completing the course.

Understanding the Difference

Structura vs. Profhilo
vs. Dermal Filler

This treatment

Profhilo® Structura

  • NAHYCO® patented HA technology
  • Injected into subcutaneous fat layer
  • Restores & repositions fat pads
  • Activates fat cell receptors biologically
  • No mechanical volume — natural repositioning
  • No foreign body response
  • 2 sessions one month apart

Related treatment

Profhilo®

  • NAHYCO® patented HA technology
  • Injected into the dermis
  • Stimulates collagen & elastin
  • Improves skin quality & hydration
  • Bio-remodelling — no volume added
  • Ideal combined with Structura
  • 2 sessions one month apart

Alternative

Dermal Filler

  • Cross-linked hyaluronic acid
  • Injected for mechanical volume
  • Adds volume to replace lost tissue
  • Immediate visual result
  • Risk of migration and overfilling
  • Foreign body response possible
  • Variable longevity 6–18 months

Who It's For

Ideal patients
for Profhilo Structura

Mid-Face Hollowing

Patients who notice the cheeks appear flatter, the under-eye hollow is more pronounced, or the face looks gaunt or tired — all caused by deflation and descent of the mid-face fat pads.

Changing Facial Shape

As the mid-face deflates, faces often appear squarer, with jowls more prominent and the jaw seemingly heavier. Structura restores the natural V-shape and mid-face projection of youth.

Skin Laxity & Descent

Patients with skin laxity in the mid-face and cheek area who want genuine structural improvement rather than surface-level tightening from skin boosters or energy treatments.

Post Weight-Loss or Ozempic Face

Rapid fat loss — including from GLP-1 medications such as Ozempic or Wegovy — can cause significant facial volume loss. Structura restores this naturally without traditional filler bulk.

The Profhilo® Range

Three treatments,
one philosophy

Face & neck

Profhilo®

The original bio-remodelling treatment for the face, neck, and décolletage. Stimulates four types of collagen and elastin for deep hydration and tightening. Pairs beautifully with Structura.

Learn more →

Body laxity

Profhilo® Body

The only injectable specifically indicated for body skin laxity — inner arms, abdomen, thighs, and knees. Includes post-treatment Body Patch and at-home Body Cream.

Learn more →

This treatment

Profhilo® Structura

Next-generation structural lifting via fat pad restoration. Clinically proven mid-face improvement in 95% of patients after the first session.

You are here

Guide Pricing

Investment in your structure

Per Session

£325

two sessions recommended — administered one month apart

Full Course

£650

two-session course — the standard protocol for optimal results

Combined with Profhilo

Bespoke

Structura + Profhilo together address both structural and skin quality ageing — ask Dr Sabrina about combined protocols

At a Glance

Treatment summary

Treatment Time

~30 minutes

Return to Work

Immediate

Recovery

Up to 24 hours

Sessions

2 (one month apart)

Results

Fast-acting

Duration

4–6 months

Common Questions

Frequently asked questions

Profhilo Structura is a next-generation injectable using patented NAHYCO technology. Rather than adding filler volume, it is injected into the subcutaneous fat layer where it activates ageing adipose fat cell receptors — restoring and repositioning the superficial fat pads that deflate and descend with age. It is clinically proven to restore mid-face fat to its original position, reversing hollowing, descent, and the squaring of facial shape.
Fillers work mechanically — they add volume by occupying space. Profhilo Structura works biologically — it targets the fat cells themselves and encourages them to restore their own volume and position. The body recognises this as a natural process rather than a foreign body, meaning no stiffness, no unnatural heaviness, and no migration risk associated with filler. The result is a subtly lifted, more contoured face rather than a volumised one.
Profhilo is injected into the dermis where it stimulates fibroblasts to regenerate collagen and elastin — improving skin quality, firmness, and hydration from the skin level. Profhilo Structura is injected deeper, into the subcutaneous layer, targeting the fat pads directly to provide structural lifting and repositioning. They address different aspects of facial ageing and are often used together for a comprehensive result.
Profhilo Structura is ideal for patients who have noticed mid-face hollowing, loss of cheek definition, pronounced nasolabial folds, or a squarer, more jowly facial appearance — all caused by age-related fat pad migration. It is also well suited to patients who have experienced facial fat loss from rapid weight loss, including those who have used GLP-1 medications such as Ozempic or Wegovy. Dr Sabrina will confirm suitability at consultation.
95% of patients noticed lasting improvements in the mid-face area after their first treatment, with that improvement sustained three months later in clinical trials. Patients typically describe a subtly lifted, more contoured facial profile — improved cheek definition, less pronounced hollows, and a more rested, youthful appearance. Results last 4–6 months, with maintenance sessions recommended to sustain and build on results.

Ready to Begin

Book your Structura consultation with Dr Sabrina

Explore the full Profhilo range: Profhilo & Profhilo Body. Or explore Polynucleotides and Radiesse for structural concerns.

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Conveniently located in Hertford — accessible from St Albans, Welwyn Garden City, Ware, Hoddesdon, Potters Bar, Hatfield & North London.